The most common human cancers are malignant neoplasms of the skin 1 , 2 . Incidence of
cutaneous melanoma is rising especially steeply, with minimal progress in non-surgical …

Background Many cases of hereditary breast cancer are due to mutations in either the
BRCA1 or the BRCA2 gene. The histopathological changes in these cancers are often …

With the advance of hybridization array technology researchers can measure expression
levels of sets of genes across different conditions and over time. Analysis of data produced by …

The BNT162b2 mRNA vaccine is highly effective against SARS-CoV-2. However, apprehension
exists that variants of concern (VOCs) may evade vaccine protection, due to evidence of …

Constantly improving gene expression profiling technologies are expected to provide
understanding and insight into cancer related cellular processes. Gene expression data is also …

This paper concerns the discovery of patterns in gene expression matrices, in which each
element gives the expression level of a given gene in a given experiment. Most existing …

Background— Apelin is among the most potent stimulators of cardiac contractility known.
However, no physiological or pathological role for apelin–angiotensin receptor-like 1 (APJ) …

The possible involvement of several transcription systems in the anticancer activity of
carotenoids is the focus of this review. Carotenoids modulate the basic mechanisms of cell …

Despite considerable excitement over the potential functional significance of copy-number
variants (CNVs), we still lack knowledge of the fine-scale architecture of the large majority of …

Array-based comparative genomic hybridization (CGH) measures copy-number variations
at multiple loci simultaneously, providing an important tool for studying cancer and …