The number of people diagnosed with Alzheimer's disease (AD) is increasing steadily as
the world population ages, thus creating a huge socio-economic burden. Current treatments …

The number of people suffering from Alzheimer's disease (AD) will increase as the world
population ages, creating a huge socio-economic burden. The three pathophysiological …

The bone morphogenetic proteins (BMPs), which are involved in bone formation and repair,
play an important role in tissue engineering. For example, BMP-9 and BMP-2, which are …

A role for tissue transglutaminase (TG2) and its substrate dual leucine zipper-bearing kinase
(DLK), an upstream component of the c-Jun N-terminal kinase (JNK) signaling pathway, …

Dual leucine zipper-bearing kinase (DLK) is a mixed-lineage kinase family member that acts
as an upstream activator of the c-Jun N-terminal kinases. As opposed to other components …

Although tissue transglutaminase (tTG) has been recognized as a mediator of apoptosis in
various experimental models, little is currently known about the molecular mechanisms by …

Biomimetic materials were developed to regulate stem cell behaviour. We have analyzed
the influence of polycaprolactone (PCL) films, functionalized with adhesive peptides derived …

Current evidence suggests that the mixed lineage kinase family member dual leucine zipper-bearing
kinase (DLK) might play a significant role in the regulation of cell growth and …

Biomaterials functionalized by adhesive peptides improve the cell–substratum interaction.
However, their influence on the response of cells to growth factors is still poorly understood. …

The bone morphogenetic proteins (BMPs) are potent osteogenic molecules that are used for
bone repair in delivery systems and in regenerative medicine. We studied the responses of …