User profiles for G. Crawford

Gregory Crawford

Duke University
Verified email at duke.edu
Cited by 66542

Defining functional DNA elements in the human genome

…, LD Ward, E Birney, GE Crawford… - Proceedings of the …, 2014 - National Acad Sciences
With the completion of the human genome sequence, attention turned to identifying and
annotating its functional DNA elements. As a complement to genetic and comparative genomics …

Liquid-crystal materials find a new order in biomedical applications

SJ Woltman, GD Jay, GP Crawford - Nature materials, 2007 - nature.com
With the maturation of the information display field, liquid-crystal materials research is
undergoing a modern-day renaissance. Devices and configurations based on liquid-crystal …

Rosacea: I. Etiology, pathogenesis, and subtype classification

GH Crawford, MT Pelle, WD James - Journal of the American Academy of …, 2004 - Elsevier
Rosacea is one of the most common conditions dermatologists treat. Rosacea is most often
characterized by transient or persistent central facial erythema, visible blood vessels, and …

[HTML][HTML] High-resolution mapping and characterization of open chromatin across the genome

…, EH Margulies, Z Weng, TS Furey, GE Crawford - Cell, 2008 - cell.com
Mapping DNase I hypersensitive (HS) sites is an accurate method of identifying the location
of genetic regulatory elements, including promoters, enhancers, silencers, insulators, and …

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

…, LJM Coin, MN Cooper, M Cornelis, G Crawford… - Nature …, 2010 - nature.com
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …

[HTML][HTML] A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults

…, M Holodniy, WA Keitel, GE Crawford… - … England Journal of …, 2005 - Mass Medical Soc
Background The incidence and severity of herpes zoster and postherpetic neuralgia increase
with age in association with a progressive decline in cell-mediated immunity to varicella–…

The ENCODE (ENCyclopedia of DNA elements) project

…, B Zhu, AD Baxevanis, TG Wolfsberg, GE Crawford… - Science, 2004 - scholarworks.bwise.kr
The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional elements
in the human genome sequence. The pilot phase of the Project is focused on a specified …

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

…, PS Chines, M Cornelis, DJ Couper, G Crawford… - Nature …, 2010 - nature.com
By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D)
and 38,987 controls of European descent and following up previously unidentified meta-…

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

…, W Wang, Z Weng, RD Green, GE Crawford… - Nature …, 2007 - nature.com
Eukaryotic gene transcription is accompanied by acetylation and methylation of nucleosomes
near promoters, but the locations and roles of histone modifications elsewhere in the …

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

…, GE Crawford, CA Crowley, HS Dashti, G Davies… - Nature …, 2018 - nature.com
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …