Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized as a
neoplastic disorder owing to the discovery of recurrent activating MAPK (RAS-RAF-MEK-ERK) …

… Elevated levels of IL-6, tumor necrosis factor (TNF), MCP-1, granulocyte colony-stimulating
factor (G-CSF), macrophage inflammatory protein 1α (MIP-1α), and soluble IL-2 receptor α (…

Lycopene is the principal pigment of the carotenoids naturally found in tomatoes and is
important not only because of the color it imparts but also because of the recognized health …

Importance A daily dose with 6 mg of dexamethasone is recommended for up to 10 days in
patients with severe and critical COVID-19, but a higher dose may benefit those with more …

The rapid repurposing of antivirals is particularly pressing during pandemics. However, rapid
assays for assessing candidate drugs typically involve in vitro screens and cell lines that do …

Background Weight reduction is essential for improving health outcomes in people with
obesity and type 2 diabetes. We assessed the efficacy and safety of tirzepatide, a glucose-…

Here, we show that microfluidic organ-on-a-chip (organ chip) cell culture technology can be
used to create in vitro human orthotopic models of non-small-cell lung cancer (NSCLC) that …

Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of
clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary (…

Neuropathic pain is difficult to diagnose and difficult to treat with certainty. So the aim of the
study was to evaluate comparative clinical efficacy of pregabaline with amitriptyline and …

… the level of ethanol (1.87 g/liter) as a consortium with an equal ratio of the different populations.
The final ethanol yield of 0.475 g of ethanol/g of cellulose consumed also corresponded …