Anaphylaxis is an acute, potential life-threatening systemic allergic reaction that may have a
wide range of clinical manifestations. Severe anaphylaxis and/or the need for repeated …

New developments in the treatment and management of phenylketonuria (PKU) as well as
advances in molecular testing have emerged since the National Institutes of Health 2000 …

Simple Summary Late-stage colorectal cancer treatment often involves chemotherapy and
radiation that can cause dose-limiting toxicity, and therefore there is great interest in …

Background The frequency of major malformations, growth retardation, and hypoplasia of
the midface and fingers, known as anticonvulsant embryopathy, is increased in infants …

Objectives. This study sought to determine the rate of familial occurrence of congenital bicuspid
aortic valve (BAV) by using echocardiography to screen family members. Background. …

… temperature-dependent equilibrium constant, K, for isotope exchange reactions involving …
equation image equation image ), the ratio K/K*, where K* is the equilibrium constant for the …

Increased use and improved methodology of carbonate clumped isotope thermometry has
greatly enhanced our ability to interrogate a suite of Earth‐system processes. However, …

Current climate trends resulting in rapid declines in sea ice and increasing water temperatures
are likely to expand the northern geographic range and duration of favorable conditions …

The effectiveness of a phenylalanine-restricted diet to improve the outcome of individuals with
phenylalanine hydroxylase deficiency (OMIM no. 261600) has been recognized since the …

The potential for carbonate clumped isotope thermometry to independently constrain both the
formation temperature of carbonate minerals and fluid oxygen isotope composition allows …