Introduction Eosinophilic esophagitis (EoE) is one of the most prevalent esophageal diseases
and the leading cause of dysphagia and food impaction in children and young adults. This …

… Some melatonin detected in the gut is of pineal origin through accumulation from circulating
sources, and the digestive tract, especially in the lower gut, might act as a store for pineal-…

Opioid receptors are widely distributed in the human body and are crucially involved in
numerous physiological processes. These include pain signaling in the central and the …

… The staining solution (0.3% cuprolinic acid and 1 M MgCl 2 in 0.025 M sodium acetate buffer,
pH 5.6) was applied for 60 minutes at room temperature, and the sections were then rinsed …

Of patients with newly diagnosed multiple myeloma, approximately 10% have dialysis-dependent
acute renal failure, with cast nephropathy, caused by monoclonal free light chains (FLC…

… M Katschinski3, … M Storr1,3, … Nine healthy male volunteers, 22–28 years of age, body
mass index 22–24 kg/m 2 , participated in the studies. None was taking any medication, and all …

… concentration 0.1 M) containing dimethyl-silapentane-sulfonate (final concentration 0.5
mM) for NMR chemical shift reference and concentration calibration, and 10 μL of 1 M sodium …

… If the time is not appropriate, the rectum accommodates to store the stool temporarily,
resulting in the dissipation of the urge and propagating contractions. Normal colonic transit in …

Inflammatory bowel disease (IBD) is a group of diseases characterized by inflammation of
the small and large intestine and primarily includes ulcerative colitis and Crohn's disease. …

The enteric nervous system contains excitatory and inhibitory neurons, which control contraction
and relaxation of smooth muscle cells as well as gastrointestinal motor activity. Little is …